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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2415928Generated: October 31, 2026

1-methyl-2-(piperazin-1-yl)-1H-benzo[d]imidazole → 9-{4-[4-(1-methyl-1H-benzimidazol-2-yl)-piperazin-1-yl]-butyl}-9H-fluorene-9-carboxylic Acid-4-fluoro-benzylamide

https://huagongshe.com/reaction/2415928

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-methyl-2-(piperazin-1-yl)-1H-benzo[d]imidazoleHCID 667551—
Reactant9-(4-bromo-butyl)-9H-fluorene-9-carboxylic acid-4-fluoro-benzylamideHCID 22636238—
Product9-{4-[4-(1-methyl-1H-benzimidazol-2-yl)-piperazin-1-yl]-butyl}-9H-fluorene-9-carboxylic Acid-4-fluoro-benzylamideHCID 22636228—

Reaction Steps

Prepared analogously to Example 1 from 9-(4-bromo-butyl)-9H-fluorene-9-carboxylic acid-4-fluoro-benzylamide and 1-methyl-2-piperazin-1-yl-1H-benzimidazole.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06821967B2
Source datasetuspto-grants-2004_11
ORD IDord-d84e51c4987449548cd297c66458690e
Source noteuspto-grants-2004_11