HCID 22636218, compound → HCID 22636314, compound

Participants

Reaction Steps

A solution of 0.08 g (0.142 mmol) of 9-[4-(4-quinolin-2-yl-piperazin-1-yl)-butyl]-9H-fluorene-9-carboxylic acid-(2-methoxycarbonyl-ethyl)-amide in 2 ml of 2N sodium hydroxide solution and 35 ml of methanol is stirred for 14 hours at ambient temperature. Then the mixture is concentrated by evaporation, diluted with water and adjusted to a pH of 5 with 1N hydrochloric acid. The precipitate formed is filtered off.

Provenance & Evidence