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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2415978Generated: November 1, 2026

9-(4-bromo-butyl)-9H-fluorene-9-carboxylic acid-3,4-difluoro-benzylamide → 9-[4-(cis-2,6-dimethyl-4-quinolin-2-yl-piperazin-1-yl)-butyl]-9H-fluorene-9-carboxylic Acid-3,4-difluoro-benzylamide

https://huagongshe.com/reaction/2415978

Reaction equation

Participants

RoleNameHCIDCharge
Reactant9-(4-bromo-butyl)-9H-fluorene-9-carboxylic acid-3,4-difluoro-benzylamideHCID 22636193—
Reactant2-(cis-3,5-Dimethyl-piperazin-1-yl)-quinolineHCID 69893100—
Product9-[4-(cis-2,6-dimethyl-4-quinolin-2-yl-piperazin-1-yl)-butyl]-9H-fluorene-9-carboxylic Acid-3,4-difluoro-benzylamideHCID 23526847—

Reaction Steps

Prepared analogously to Example 2 from 9-(4-bromo-butyl)-9H-fluorene-9-carboxylic acid-3,4-difluoro-benzylamide and 2-(cis-3,5-dimethyl-piperazin-1-yl)-quinoline.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06821967B2
Source datasetuspto-grants-2004_11
ORD IDord-4ba933b999b54434a426a46cf86842ca
Source noteuspto-grants-2004_11