2-Amino-5-chlorobenzonitrile → HCID 86610494, compound

HRID 2416198Notes

Reaction equation

HRID 2416198 reaction equation
[NH2:1][C:2]1[CH:9]=[CH:8][C:7]([Cl:10])=[CH:6][C:3]=1[C:4]#[N:5].[N:11]1[CH:16]=[CH:15][C:14]([C:17]2([CH2:22][C:23](O)=[O:24])[NH:21][CH:20]=[CH:19][S:18]2)=[CH:13][CH:12]=1>>[C:4]([C:3]1[CH:6]=[C:7]([Cl:10])[CH:8]=[CH:9][C:2]=1[NH:1][C:23](=[O:24])[CH2:22][C:17]1([C:14]2[CH:15]=[CH:16][N:11]=[CH:12][CH:13]=2)[NH:21][CH:20]=[CH:19][S:18]1)#[N:5]

Participants

3

Reactant 2

HCID 800192-Amino-5-chlorobenzonitrileHCID 86610488HCID 86610488, compound

Product 1

HCID 86610494HCID 86610494, compound

Procedure

This compound was prepared according to the method described in Example 1c by employing 2-amino-5-chlorobenzonitrile (Aldrich) and 2-(4-pyridyl)-thiazole acetic acid (Example 1, Step b). Mp: 164-166° C. MS m/z: 355.0 (M+1). Calc'd for C17H11ClN4OS: 354.03.

Workup

  1. customThis compound was prepared

Sources & evidence

ORD record
ord-b108c867523349af930d591faf0b3b73
Source dataset
uspto-grants-2004_11
Patent number
US06822097B1

Reaction notes

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