Pyrrolidine → HCID 22638679, compound

HRID 2416222Notes

Reaction equation

HRID 2416222 reaction equation
[N:1]1[CH:6]=[CH:5][C:4]([C:7]2[S:8][CH:9]=[C:10]([C:12]3[C:13](=[O:24])[NH:14][C:15]4[C:20]([CH:21]=3)=[CH:19][CH:18]=[C:17]([CH:22]=O)[CH:16]=4)[N:11]=2)=[CH:3][CH:2]=1.[NH:25]1[CH2:29][CH2:28][CH2:27][CH2:26]1>>[N:1]1[CH:6]=[CH:5][C:4]([C:7]2[S:8][CH:9]=[C:10]([C:12]3[C:13](=[O:24])[NH:14][C:15]4[C:20]([CH:21]=3)=[CH:19][CH:18]=[C:17]([CH2:22][N:25]3[CH2:29][CH2:28][CH2:27][CH2:26]3)[CH:16]=4)[N:11]=2)=[CH:3][CH:2]=1

Participants

3

Reactant 2

HCID 31268PyrrolidineHCID 22638533HCID 22638533, compound

Product 1

HCID 22638679HCID 22638679, compound

Procedure

This compound was prepared according to the method described in example 8768 employing 3-(2-pyridin-4-yl-thiazol-4-yl)-1H-quinolin-2-one-7-carbaldehyde and pyrrolidine to give a yellow solid. MS m/z: 389.2 (M+1).

Workup

  1. customThis compound was prepared
  2. customto give a yellow solid

Sources & evidence

ORD record
ord-c0263b16a9ff45198e2de5c41b252301
Source dataset
uspto-grants-2004_11
Patent number
US06822097B1

Reaction notes

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