Piperidin-4-ol → HCID 22638669, compound

HRID 2416226Notes

Reaction equation

HRID 2416226 reaction equation
[N:1]1[CH:6]=[CH:5][C:4]([C:7]2[S:8][CH:9]=[C:10]([C:12]3[C:13](=[O:24])[NH:14][C:15]4[C:20]([CH:21]=3)=[CH:19][CH:18]=[C:17]([CH:22]=O)[CH:16]=4)[N:11]=2)=[CH:3][CH:2]=1.[OH:25][CH:26]1[CH2:31][CH2:30][NH:29][CH2:28][CH2:27]1>>[OH:25][CH:26]1[CH2:31][CH2:30][N:29]([CH2:22][C:17]2[CH:16]=[C:15]3[C:20]([CH:21]=[C:12]([C:10]4[N:11]=[C:7]([C:4]5[CH:3]=[CH:2][N:1]=[CH:6][CH:5]=5)[S:8][CH:9]=4)[C:13](=[O:24])[NH:14]3)=[CH:19][CH:18]=2)[CH2:28][CH2:27]1

Participants

3

Reactant 2

HCID 79341Piperidin-4-olHCID 22638533HCID 22638533, compound

Product 1

HCID 22638669HCID 22638669, compound

Procedure

This compound was prepared according to the method described in example 8768 employing 3-(2-pyridin-4-yl-thiazol-4-yl)-1H-quinolin-2-one-7-carbaldehyde and 4-hydroxypiperidine. To give a yellow solid. MS m/z: 419.0 (M+1).

Workup

  1. customThis compound was prepared
  2. customTo give a yellow solid

Sources & evidence

ORD record
ord-f5ff644309d94450a7846296507d6a53
Source dataset
uspto-grants-2004_11
Patent number
US06822097B1

Reaction notes

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