HuagongsheHuagongshe Chemistry Print Report · For research reference only
Butane-2-sulfonyl chloride → Butane-2-sulphonic acid 3'-amino-4-(2,4-diamino-pvrimidin-5-ylmethyl)-6-ethoxy-biphenyl-2-yl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Butane-2-sulfonyl chloride | HCID 2757336 | — |
| Reactant | 3'-Amino-4-(2,4-diamino-pyrimidin-5-ylmethyl)-6-ethoxy-biphenyl-2-ol | HCID 22636979 | — |
| Product | Butane-2-sulphonic acid 3'-amino-4-(2,4-diamino-pvrimidin-5-ylmethyl)-6-ethoxy-biphenyl-2-yl ester | HCID 17937242 | 67.4% |
Reaction Steps
Starting from 3′-amino-4-(2,4-diamino-pyrimidin-5-ylmethyl)-6-ethoxy-biphenyl-2-ol (176 mg; 0.50 mmol) and sec-butyl-sulphonyl chloride (94 mg; 0.60 mmol), 159 mg of the title compound are isolated as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06821980B1 |
| Source dataset | uspto-grants-2004_11 |
| ORD ID | ord-c798dad9aaa1482c8ab1f7adcd2829fb |
| Source note | uspto-grants-2004_11 |