HuagongsheHuagongshe Chemistry Print Report · For research reference only
Morpholine, 4-(2-chloroethyl)-, hydrochloride (1:1) → HCID 22636910, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Morpholine, 4-(2-chloroethyl)-, hydrochloride (1:1) | HCID 77210 | — |
| Reactant | HCID 22636882 | HCID 22636882 | — |
| Reactant | HCID 22637022 | HCID 22637022 | — |
| Product | HCID 22636910 | HCID 22636910 | — |
Reaction Steps
Starting from 2′-cyclopropylmethoxy-4′-(2,4-diamino-pyrimidin-5-ylmethyl)-6′ethoxy-biphenyl-4-ol (example 8h) (300 mg; 0.74 mmol) and 4-(2-chloroethyl)-morpholine hydrochloride (170 mg; 0.89 mmol), 129 mg (25%) 5-[2-cyclopropylmethoxy-6-ethoxy-4′-(2-morpholin-4-yl-ethoxy)-biphenyl-4-ylmethyl]-pyrimidine-2,4-diamine are obtained as a colourless powder.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06821980B1 |
| Source dataset | uspto-grants-2004_11 |
| ORD ID | ord-32099499b39343ae8b1baf4827c048e1 |
| Source note | uspto-grants-2004_11 |