HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetyl chloride → 1-(4-(1-(cyclopropylmethyl)-2-neopentyl-1H-benzo[d]imidazol-5-ylsulfonyl)-4-(hydroxymethyl)piperidin-1-yl)ethanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetyl chloride | HCID 6367 | — |
| Reactant | (4-(1-(cyclopropylmethyl)-2-neopentyl-1H-benzo[d]imidazol-5-ylsulfonyl)piperidin-4-yl)methanol | HCID 58513575 | — |
| Product | 1-(4-(1-(cyclopropylmethyl)-2-neopentyl-1H-benzo[d]imidazol-5-ylsulfonyl)-4-(hydroxymethyl)piperidin-1-yl)ethanone | HCID 46851884 | — |
Reaction Steps
The title compound was prepared according to the procedure described in STEP D of Example 6 using (4-(1-(cyclopropylmethyl)-2-neopentyl-1H-benzo[d]imidazol-5-ylsulfonyl)piperidin-4-yl)methanol (STEP G) and acetyl chloride instead of methanesulfonyl chloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08653063B2 |
| Source dataset | uspto-grants-2014_02 |
| ORD ID | ord-dfcae91e1c794cffacb6fb9e06f70a39 |
| Source note | uspto-grants-2014_02 |