2-Bromopyridine → HCID 22630853, compound

HRID 2416522Notes

Reaction equation

Br[C:2]1[S:6][CH:5]=[C:4]([CH:7]=[O:8])[CH:3]=1.Br[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][N:11]=1.BrC1C=CC(C=O)=C(F)C=1.BrC1N=CC=CN=1>>[N:11]1[CH:12]=[CH:13][CH:14]=[CH:15][C:10]=1[C:2]1[S:6][CH:5]=[C:4]([CH:7]=[O:8])[CH:3]=1

Participants

Reactant 4

HCID 79732-Bromopyridine

HCID 783452-Bromopyrimidine

HCID 1435174-Bromo-2-fluorobenzaldehyde

HCID 122848945-Bromothiophene-3-carbaldehyde

Product 1

HCID 22630853HCID 22630853, compound

Procedure

The title compound is prepared by a procedure analogous to Reference Example 15 by substituting 5-bromo-3-thiophenecarboxaldehyde (prepared as described in Chem. Pharm. Bull. 1999, 47,1393) and 2-bromopyridine, respectively, for the 4-bromo-2-fluorobenzaldehyde and 2-bromopyrimidine of Reference Example 15. MS 190 (M+H)+.

Sources & evidence

ORD record: ord-bcb0ade391374cffa51f91b813331c15
Source dataset: uspto-grants-2004_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06825170B2

Reaction notes

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