HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chloropyrazine → 5-Pyrazinyl-3-thiophenecarboxaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chloropyrazine | HCID 73277 | — |
| Reactant | 2-Bromopyrimidine | HCID 78345 | — |
| Reactant | 4-Bromo-2-fluorobenzaldehyde | HCID 143517 | — |
| Reactant | 5-Bromothiophene-3-carbaldehyde | HCID 12284894 | — |
| Product | 5-Pyrazinyl-3-thiophenecarboxaldehyde | HCID 86590275 | — |
Reaction Steps
The title compound is prepared by a procedure analogous to Reference Example 15 by substituting 5-bromo-3-thiophenecarboxaldehyde (prepared as described in Chem. Pharm. Bull. 1999, 47,1393) and chloropyrazine, respectively, for the 4-bromo-2-fluorobenzaldehyde and 2-bromopyrimidine of Reference Example 15. MS 191 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06825170B2 |
| Source dataset | uspto-grants-2004_11 |
| ORD ID | ord-f128ac031bf14c27890b8e8ff2981759 |
| Source note | uspto-grants-2004_11 |