3-Quinolinecarboxaldehyde → HCID 72639244, compound

HRID 2416560Notes

Reaction equation

HRID 2416560 reaction equation
[F:1][C:2]([F:12])([F:11])[C:3]1[N:8]=[CH:7][C:6]([CH:9]=O)=[CH:5][N:4]=1.N1C2C(=CC=CC=2)C=[C:15]([CH:23]=[O:24])C=1>>[F:1][C:2]([F:12])([F:11])[C:3]1[N:8]=[CH:7][C:6]([CH:9]=[CH:15][CH:23]=[O:24])=[CH:5][N:4]=1

Participants

3

Reactant 2

HCID 836413-QuinolinecarboxaldehydeHCID 177509412-(Trifluoromethyl)pyrimidine-5-carbaldehyde

Product 1

HCID 72639244HCID 72639244, compound

Procedure

The title compound was prepared by a procedure analogous to Reference Example 7 by substituting 2-trifluoromethyl-5-pyrimidinecarboxaldehyde (prepared as described in WO0066566) for the 3-quinolinecarboxaldehyde of Reference Example 7. MS 203 (M+H)+.

Sources & evidence

ORD record
ord-8ff075df57cd449995c581ca9a161316
Source dataset
uspto-grants-2004_11
Patent number
US06825172B2

Reaction notes

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