Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Benzylamine | HCID 7504 | — |
| Reactant | HCID 22631339 | HCID 22631339 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 22631323 | HCID 22631323 | — |
Reaction Steps
2.82 g (8.86 mmol) of 1-chloro-6-iodo-7-methoxyisoquinoline was added to 15 ml of benzylamine, and they were stirred at 140° C. overnight. After the treatment with dichloromethane as the extraction solvent in an ordinary manner, the obtained crude product was purified by the silica gel column chromatography to obtain the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06825181B1 |
|---|
| Source dataset | uspto-grants-2004_11 |
|---|
| ORD ID | ord-e9b88924dfd04336a8deecb520be824f |
|---|
| Source note | uspto-grants-2004_11 |
|---|
