Hydrochloric Acid → HCID 22478527, compound

HRID 2416601Notes

Reaction equation

HRID 2416601 reaction equation
COC[O:4][C:5]1[CH:6]=[C:7]([N:11]2[CH2:17][CH2:16][CH2:15][NH:14][CH2:13][CH2:12]2)[CH:8]=[N:9][CH:10]=1.[ClH:18]>>[ClH:18].[OH:4][C:5]1[CH:6]=[C:7]([N:11]2[CH2:17][CH2:16][CH2:15][NH:14][CH2:13][CH2:12]2)[CH:8]=[N:9][CH:10]=1

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 10609926HCID 10609926, compound

Product 1

HCID 22478527HCID 22478527, compound

Procedure

1-(5-Methoxymethoxy-3-pyridyl)-homopiperazine (8.5 g, 35.9 mmol) was stirred in hydrochloric acid (4 M, 100 ml) at room temperature for 1 h. The excess of hydrochloric acid was evaporated. A crystaline compound was obtained by triturating with a mixture of 5% methanol and ether. Yield 9.56 g, 100%. Mp 290-300° C.

Workup

  1. customThe excess of hydrochloric acid was evaporated
  2. customA crystaline compound was obtained
  3. customby triturating with a mixture of 5% methanol and ether

Sources & evidence

ORD record
ord-144b3eab0e8f4f9d9fb1e11459f06150
Source dataset
uspto-grants-2004_11
Patent number
US06825189B1

Reaction notes

Loading…