HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Acetate → HCID 22632742, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Acetate | HCID 517045 | — |
| Reactant | HCID 22632740 | HCID 22632740 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 22632742 | HCID 22632742 | 33.1% |
Reaction Steps
2-(2-Chloro-4-pyridyl)-4-phenyl-4H-1,3,4-oxadiazine-5(6H)-one hydrochloride (780 mg, 2.4 mmol) obtained in Example 12 was hydrogenated in a usual manner in methanol in the presence of sodium acetate and 10% palladium/carbon catalyst, to give the title compound (230 mg, yield 33%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06825192B1 |
| Source dataset | uspto-grants-2004_11 |
| ORD ID | ord-94d7cc01c10341d0927b3bd4f2a59b8c |
| Source note | uspto-grants-2004_11 |