HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 2-Methyl-1-phenylpiperaZine hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 4-Boc-2-methyl-1-phenylpiperazine | HCID 22633071 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | 2-Methyl-1-phenylpiperaZine hydrochloride | HCID 22633059 | — |
Reaction Steps
(±)-tert-Butyl 3-methyl-4-phenylpiperazine-1-carboxylate (142 mg) was dissolved in 4N hydrogen chloride in ethyl acetate (5 ml). After stirring for 15 minutes, the solvent was removed under reduced pressure to give the title compound as a slightly yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06825200B1 |
| Source dataset | uspto-grants-2004_11 |
| ORD ID | ord-bad87fa887ec45f383499b68be82f86c |
| Source note | uspto-grants-2004_11 |