Hydrochloric Acid → HCID 46852043, compound

Participants

Reaction Steps

(S)—N,N-dimethyl-2-(5-(1-methylpyrrolidin-3-ylsulfonyl)-2-neopentyl-1H-benzo[d]imidazol-1-yl)ethanamine (STEP G, 704 mg, 1.73 mmol) was dissolved in ethanol (2 mL). The resulting solution was added 4 mol/L hydrogen chloride in ethyl acetate solution (857 microL, 3.43 mmol) at room temperature. The whole was concentrated in vacuo. The resulting solid was recrystallized from ethanol (4 mL) to give the title compound (413 mg, 50%).

Provenance & Evidence