HCID 54434818, compound → HCID 22632123, compound

HRID 2416713Notes

Reaction equation

HRID 2416713 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][N:6]=[C:5]([NH:9][CH2:10][CH2:11][CH2:12][O:13][C:14]2[CH:30]=[CH:29][C:17]3[CH2:18][CH:19]([CH2:24][C:25]([O:27]C)=[O:26])[C:20](=[O:23])[NH:21][CH2:22][C:16]=3[CH:15]=2)[CH:4]=1.N1C=CC=CC=1NCCCOC1C=CC2CC(CC(OCC)=O)C(=O)NCC=2C=1>O>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][N:6]=[C:5]([NH:9][CH2:10][CH2:11][CH2:12][O:13][C:14]2[CH:30]=[CH:29][C:17]3[CH2:18][CH:19]([CH2:24][C:25]([OH:27])=[O:26])[C:20](=[O:23])[NH:21][CH2:22][C:16]=3[CH:15]=2)[CH:4]=1

Participants

4

Reactant 2

HCID 54434818HCID 54434818, compoundHCID 57022123HCID 57022123, compound

Product 1

HCID 22632123HCID 22632123, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

According to the procedure of Example 1(c), except substituting methyl (±)-8-[3-[(4-methoxy-2-pyridyl)amino]-1-propyloxy]-3-oxo-2,3,4,5-tetrahydro-1H-2-benzazepine-4-acetate for the ethyl (±)-8-[3-(2-pyridylamino)-1-propyloxy]-3-oxo-2,3,4,5-tetrahydro-1H-2-benzazepine-4-acetate, the title compound was prepared as an off-white solid: MS (ES) m/e 400.3 (M+H)+. Anal. Calcd for C21H25N3O5.0.75 H2O: C, 61.08; H, 6.47; N, 10.18. Found: C, 61.15; H, 6.20; N, 10.12.

Sources & evidence

ORD record
ord-6fad31d05b294de394d0dffbf9379aef
Source dataset
uspto-grants-2004_11
Patent number
US06825188B2

Reaction notes

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