Hydrochloric Acid → HCID 22632220, compound

HRID 2416721Notes

Reaction equation

HRID 2416721 reaction equation
[CH3:1][C:2]1[CH:7]=[C:6]([CH3:8])[N:5]=[C:4]([NH:9][CH2:10][CH2:11][CH2:12][O:13][C:14]2[CH:31]=[CH:30][C:17]3[CH2:18][CH:19]([CH2:25][C:26]([O:28]C)=[O:27])[C:20](=[O:24])[N:21]([CH3:23])[CH2:22][C:16]=3[CH:15]=2)[CH:3]=1.N1C=CC=CC=1NCCCOC1C=CC2CC(CC(OCC)=O)C(=O)NCC=2C=1.Cl>O>[CH3:1][C:2]1[CH:7]=[C:6]([CH3:8])[N:5]=[C:4]([NH:9][CH2:10][CH2:11][CH2:12][O:13][C:14]2[CH:31]=[CH:30][C:17]3[CH2:18][CH:19]([CH2:25][C:26]([OH:28])=[O:27])[C:20](=[O:24])[N:21]([CH3:23])[CH2:22][C:16]=3[CH:15]=2)[CH:3]=1

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 54076524HCID 54076524, compoundHCID 54434818HCID 54434818, compound

Product 1

HCID 22632220HCID 22632220, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

According to the procedure of Example 1(c), except substituting methyl (±)-8-[3-[(4,6-dimethylpyridin-2-yl)amino]-1-propyloxy]-2-methyl-3-oxo-2,3,4,5-tetrahydro-1H-2-benzazepine-4-acetate for the ethyl (±)-8-[3-(2-pyridylamino)-1-propyloxy]-3-oxo-2,3,4,5-tetrahydro-1H-2-benzazepine-4-acetate, the title compound was prepared as a white solid: MS (ES) m/e 412.2 (M+H)+. Anal. Calcd for C23H29N3O4.0.5 HCl. 0.25 H2O: C, 63.62; H, 6.96; N, 9.68. Found: C, 63.62; H, 6.96; N, 9.69.

Sources & evidence

ORD record
ord-f17b65fdc3534bf187593fbf5c061fd4
Source dataset
uspto-grants-2004_11
Patent number
US06825188B2

Reaction notes

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