HCID 54296195, compound → HCID 22632200, compound

HRID 2416722Notes

Reaction equation

HRID 2416722 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][N:5]=[C:4]([NH:8][CH2:9][CH2:10][CH2:11][O:12][C:13]2[CH:30]=[CH:29][C:16]3[CH2:17][CH:18]([CH2:24][C:25]([O:27]C)=[O:26])[C:19](=[O:23])[N:20]([CH3:22])[CH2:21][C:15]=3[CH:14]=2)[CH:3]=1.N1C=CC=CC=1NCCCOC1C=CC2CC(CC(OCC)=O)C(=O)NCC=2C=1>>[NH2:1][C:2]1[CH:7]=[CH:6][N:5]=[C:4]([NH:8][CH2:9][CH2:10][CH2:11][O:12][C:13]2[CH:30]=[CH:29][C:16]3[CH2:17][CH:18]([CH2:24][C:25]([OH:27])=[O:26])[C:19](=[O:23])[N:20]([CH3:22])[CH2:21][C:15]=3[CH:14]=2)[CH:3]=1

Participants

3

Reactant 2

HCID 54296195HCID 54296195, compoundHCID 54434818HCID 54434818, compound

Product 1

HCID 22632200HCID 22632200, compound

Procedure

According to the procedure of Example 1(c), except substituting methyl (±)-8-[3-(4-aminopyridin-2-ylamino)-1-propyloxy]-2-methyl-3-oxo-2,3,4,5-tetrahydro-1H-2-benzazepine-4-acetate for the ethyl (±)-8-[3-[2-pyridylamino)-1-propyloxy]-3-oxo-2,3,4,5-tetrahydro-1H-2-benzazepine-4-acetate, the title compound was prepared as a white solid: MS (ES) m/e 399 (M+H)+. Anal. Calcd for C21H26N4O4.1.5CF3CO2H.0.125H2O: C, 50.62: H, 4.91; N, 9.83. Found: C, 50.63; H 5.26; N, 9.90.

Sources & evidence

ORD record
ord-02bdcf8c4322453795d3f43aeb1e5f7a
Source dataset
uspto-grants-2004_11
Patent number
US06825188B2

Reaction notes

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