Hydrochloric Acid → HCID 54443000, compound

Participants

Reaction Steps

According to the procedure of Example 1(c), except substituting methyl (R)-8-[3-[(4-amino-2-pyridyl)amino]-1-propyloxy]-3-oxo-2,3,4,5-tetrahydro-1H-2-benzazepine-4-acetate for the ethyl (±)-8-[3-(2-pyridylamino)-1-propyloxy]-3-oxo-2,3,4,5-tetrahydro-1H-2-benzazepine-4-acetate, the title compound was prepared as an off-white solid: [α]D23+74.97° (c 1.45, MeOH); MS (ES) m/e 385.4 (M+H)+. Anal. Calcd for C20H24N4O4. HCl.1.5 H2O: C, 53.63; H, 6.30; N, 12.50. Found: C, 53.87; H, 6.13; N, 12.42.

Provenance & Evidence