1-Bromo-2-butyne → HCID 131724675, compound

HRID 2417281Notes

Reaction equation

HRID 2417281 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[CH:9]([S:15][C:16]1[CH:21]=[CH:20][C:19]([OH:22])=[CH:18][CH:17]=1)[C:10]([O:12][CH2:13][CH3:14])=[O:11].Br[CH2:24][C:25]#[C:26][CH3:27]>>[CH2:13]([O:12][C:10](=[O:11])[CH:9]([C:4]1[CH:5]=[CH:6][CH:7]=[CH:8][C:3]=1[O:2][CH3:1])[S:15][C:16]1[CH:21]=[CH:20][C:19]([O:22][CH2:24][C:25]#[C:26][CH3:27])=[CH:18][CH:17]=1)[CH3:14]

Participants

3

Reactant 2

HCID 27568621-Bromo-2-butyneHCID 90750084HCID 90750084, compound

Product 1

HCID 131724675HCID 131724675, compoundYield 87%

Procedure

Ethyl(2-methoxyphenyl){[4-(2-butynyloxy)phenyl]sulfanyl}acetate was prepared according to the general method as outlined in example 1 (step 2), starting from ethyl (2-methoxyphenyl)[(4-hydroxyphenyl)sulfanyl]acetate (3.2 g, 10 mmol) and 1-bromo-2-butyne (1.5 g, 11.2 mmol); 3.2 g clear oil. Yield 87%; MS(EI): 371 (M+H)+

Sources & evidence

ORD record
ord-95a8241e97fb40fe98148373f1f00d34
Source dataset
uspto-grants-2004_11
Patent number
US06825354B2

Reaction notes

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