Boronic Acid → 2-Propyloxy-5,6,7,8-tetrahydro-5,5,8,8-tetra-methylnaphthylboronic acid

HRID 2417333Notes

Reaction equation

HRID 2417333 reaction equation
Br[C:2]1[C:3]([O:16][CH2:17][CH2:18][CH3:19])=[CH:4][C:5]2[C:6]([CH3:15])([CH3:14])[CH2:7][CH2:8][C:9]([CH3:13])([CH3:12])[C:10]=2[CH:11]=1.[BH:20]([OH:22])[OH:21]>>[CH2:17]([O:16][C:3]1[CH:2]=[CH:11][C:10]2[C:9]([CH3:13])([CH3:12])[CH2:8][CH2:7][C:6]([CH3:15])([CH3:14])[C:5]=2[C:4]=1[B:20]([OH:22])[OH:21])[CH2:18][CH3:19]

Participants

3

Reactant 2

HCID 61668Boronic AcidHCID 222527532-Bromo-3-propoxy-5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-naphthalene

Product 1

HCID 226346572-Propyloxy-5,6,7,8-tetrahydro-5,5,8,8-tetra-methylnaphthylboronic acid

Procedure

In a similar manner to Example 3(a), by reaction of 8 g (24.6 mmol) of 3-bromo-2-propyloxy-5,6,7,8-tetrahydro-5,5,8,8-tetramethylnaphthalene, 5.7 g (80%) of the expected boronic acid are obtained, with a melting point of 138-9° C.

Workup

  1. customare obtained, with a melting point of 138-9° C.

Sources & evidence

ORD record
ord-790107d14227438cb80bfc7d54f4a4c2
Source dataset
uspto-grants-2004_11
Patent number
US06825360B1

Reaction notes

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