反应详情

温度

70 °C

4-amino-benzamidine mono HCl salt (17.2 mg, 0.1 mmole) was suspended in acetonitrile (1 mL). The suspension was treated with 3-chlorobenzaldehyde (14.0 mg, 0.1 mmole) and indene(11.6 mg, 0.1 mmole). Indium triflate (11.2 mg, 0.02 mmole) was added and the reaction was heated at 70° C. for 24 hours. The desired product was purified using reverse phase HPLC. Mass spectrum: 374(M+1).

1. customThe desired product was purified