HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 69892862, compound → 4-[2-(2-Carbamimidoyl-5,6a,7,11b-tetrahydro-6H-indeno[2,1-c]quinolin-6-yl)-5-hydroxy-4-methoxy-phenoxy]-benzoic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 69892862 | HCID 69892862 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 4-[2-(2-Carbamimidoyl-5,6a,7,11b-tetrahydro-6H-indeno[2,1-c]quinolin-6-yl)-5-hydroxy-4-methoxy-phenoxy]-benzoic acid methyl ester | HCID 69895029 | — |
Reaction Steps
A solution of 4-[5-Benzyloxy-2-(2-carbamimidoyl-5,6a,7,11b-tetrahydro-6H-indeno[2,1-c]quinolin-6-yl)-4-methoxy-phenoxy]-benzoic acid methyl ester (63 mg, 0.1 mmol) in 2 mL of MeOH was hydrogenated overnight using 10%Pd—C (20 mg) to give 4-[2-(2-Carbamimidoyl-5,6a,7,11b-tetrahydro-6H-indeno[2,1-c]quinolin-6-yl)-5-hydroxy-4-methoxy-phenoxy]-benzoic acid methyl ester that was used without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06825208B2 |
| Source dataset | uspto-grants-2004_11 |
| ORD ID | ord-bad5613202ea469db016a08ffe7ee3fc |
| Source note | uspto-grants-2004_11 |