HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isobutylamine → HCID 69892952, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isobutylamine | HCID 6558 | — |
| Reactant | Benzotriazol-1-yloxy-tris(dimethylamino)phosphonium hexafluorophosphate | HCID 151348 | — |
| Reactant | HCID 22633146 | HCID 22633146 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 69892952 | HCID 69892952 | — |
Reaction Steps
A mixture of 2′-(2-Carbamimidoyl-5,6a,7,11b-tetrahydro-6H-indeno[2,1-c]quinolin-6-yl)-5′-hydroxy-2,4′-dimethoxy-biphenyl-4-carboxylic acid (10.7 mg, 0.02 mmol), BOP, (0.04 mmol), diidopropylethylamine (10.3 mg, 0.08 mmol) and isobutylamine (4.4 mg, 0.06 mmol) in DMF was allowed to react at room temperature. Example 235 was purified by HPLC. Mass Spectrum: 591 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06825208B2 |
| Source dataset | uspto-grants-2004_11 |
| ORD ID | ord-64cbb2c405b24c6f8319cf50b1b2c2f8 |
| Source note | uspto-grants-2004_11 |