Hydrochloric Acid → HCID 69817703, compound

Participants

Reaction Steps

tert-Butyl N-[(1S)-2-hydroxy-1-[4-[[(1-methyl-1H-pyrrol-2-yl)carbonyl]amino]benzyl]ethyl]-N-[(2S)-2-hydroxy-3-phenoxypropyl]carbamate (158 mg) was dissolved in 4N hydrogen chloride in ethanol (2.0 ml) and the solution was stirred at room temperature for 2 hours. The solvent was removed by evaporation and the residual solid was dried under reduced pressure to give N-[4-[(2S)-3-hydroxy-2-[[(2S)-2-hydroxy-3-phenoxypropyl]amino]propyl]phenyl]-1-methyl-1H-pyrrole-2-carboxamide hydrochloride (125 mg) as a pale orange crystalline solid.

Provenance & Evidence