HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 241745Generated: October 26, 2026
Ethanolamine → 2-[2-(4-Nitro-phenyl)-ethylamino]-ethanol
https://huagongshe.com/reaction/241745
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Ethanolamine | HCID 700 | — |
| Reactant | 4-Nitrophenethyl bromide | HCID 79266 | — |
| Product | 2-[2-(4-Nitro-phenyl)-ethylamino]-ethanol | HCID 22722744 | — |
Reaction Steps
A mixture of 1-(2-bromo-ethyl)-4-nitro-benzene (86.9 mmoles) and 2-amino-ethanol (869 mmoles) is heated at 150° C. under microwave activation for 10 minutes. The reaction mixture is evaporated to dryness and the residue obtained is purified on silica gel (SiO2; gradient DCM/MeOH) to yield the title product, which is used directly in the next Step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08653073B2 |
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| Source dataset | uspto-grants-2014_02 |
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| ORD ID | ord-a45a2c6abdd64f37bd40b46e080c119b |
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| Source note | uspto-grants-2014_02 |
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