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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2417496Generated: October 25, 2026

Ethyl 5-Chloropyridine-2-carboxylate → 5-chloropyridin-2-carboxylic Acid Hydrochloride

https://huagongshe.com/reaction/2417496

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 5-Chloropyridine-2-carboxylateHCID 15414989—
SolventHydrochloric AcidHCID 313—
Product5-chloropyridin-2-carboxylic Acid HydrochlorideHCID 67175809—

Reaction Conditions

Temperature70 °C

Reaction Steps

250 mg (1.35 mmol) of ethyl 5-chloropyridin-2-carboxylate was dissolved in 6 N hydrochloric acid, and the obtained solution was stirred at 70° C. for 2 hours. The solvent was evaporated to obtain the crude product.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06825191B2
Source datasetuspto-grants-2004_11
ORD IDord-873face2c133466e8e5ea186d25118e3
Source noteuspto-grants-2004_11