Tributyltin azide → HCID 178519602, compound

Participants

Reaction Conditions

Reaction Steps

30 mg (0.059 mmol) of 4-(4-chlorobenzoyl)-8-cyano-1-[4-(pyrrolidinylcarbonyl)benzyl]-1,3,4,5-tetrahydrobenzo[e][1,4]diazepin-2-on was dissolved in 2 ml of toluene. 0.032 ml (0.11 mmol) of tributyltin azide was added to the obtained solution, and they were stirred at 120° C. for 6 hours. After the treatment with ethyl acetate as the extracting solvent by an ordinary method, the solvent was evaporated and the obtained crude product was treated in the same manner as in Step 3 in Example 1 to obtain the title compound.

Provenance & Evidence