Methyl iodide → HCID 22632485, compound

Participants

Reaction Steps

12 mg (0.019 mmol) of 6-chloro-4-(4-chlorobenzoyl)-1-[4-(1-methyl-4,5-dihydro-1H-imidazol-2-yl)benzyl]-1,3,4,5-tetrahydrobenzo[e][1,4]-diazepin-2-on trifluoroacetate was dissolved in 5 ml of acetonitrile. 5 mg (0.036 mmol) of potassium carbonate and 0.010 ml of methyl iodide were added to the obtained solution, and they were stirred at room temperature for 4 hours. The solvent was evaporated, and the obtained crude product was treated in the same manner as in step 3 in Example 1 to obtain the title compound.

Provenance & Evidence