Hydrochloric Acid → HCID 86739609, compound

HRID 2417580Notes

Reaction equation

HRID 2417580 reaction equation
[ClH:1].CC1(C)[NH:7][CH:6]([P:8]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)(=[O:10])[OH:9])[C:5]([CH3:18])([CH3:17])[S:4]1.Cl>O>[ClH:1].[NH2:7][CH:6]([P:8]([C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)(=[O:9])[OH:10])[C:5]([SH:4])([CH3:18])[CH3:17]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 70512455HCID 70512455, compound

Product 1

HCID 86739609HCID 86739609, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

0.3 g of DL-(2,2,5,5-tetramethyl-4-thiazolidinyl)phenylphosphinic acid hydrochloride (prepared as described in Example 7) was suspended in boiling water and concentrated hydrochloric acid was added until a solution had formed. The solution was filtered and the filtrate was evaporated to dryness under reduced pressure. The solid residue was recrystallized from 3N hydrochloric acid to give DL-(1-amino-2-mercapto-2-methylpropyl)phenylphosphinic acid hydrochloride of melting point 190°-192° C. (decomposition).

Workup

  1. additionwas added until a solution
  2. customhad formed
  3. filtrationThe solution was filtered
  4. customthe filtrate was evaporated to dryness under reduced pressure
  5. customThe solid residue was recrystallized from 3N hydrochloric acid

Sources & evidence

ORD record
ord-b6acc727cd124299a9db55af08bf359d
Source dataset
uspto-grants-1984_09
Patent number
US04469686

Reaction notes

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