Acetic Anhydride → HCID 54503292, compound

HRID 2417864Notes

Reaction equation

HRID 2417864 reaction equation
[C@@H:1]1([O:12][C@@H:13]2[C@@H:26]([CH2:27][OH:28])[O:25][C@@H:16]([S:17][C:18]3[CH:23]=[CH:22][C:21]([NH2:24])=[CH:20][CH:19]=3)[C@H:15]([OH:29])[C@H:14]2[OH:30])[O:9][C@H:8]([CH2:10][OH:11])[C@@H:6]([OH:7])[C@H:4]([OH:5])[C@H:2]1[OH:3].[C:31](OC(=O)C)(=[O:33])[CH3:32]>O>[C@@H:1]1([O:12][C@@H:13]2[C@@H:26]([CH2:27][OH:28])[O:25][C@@H:16]([S:17][C:18]3[CH:19]=[CH:20][C:21]([NH:24][C:31](=[O:33])[CH3:32])=[CH:22][CH:23]=3)[C@H:15]([OH:29])[C@H:14]2[OH:30])[O:9][C@H:8]([CH2:10][OH:11])[C@@H:6]([OH:7])[C@H:4]([OH:5])[C@H:2]1[OH:3]

Participants

4

Reactant 2

HCID 7918Acetic AnhydrideHCID 54268764HCID 54268764, compound

Product 1

HCID 54503292HCID 54503292, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

To a solution of 1.36 g of 4-aminophenyl 4-O-(β-D-glucopyranosyl)-1-thio-β-D-glucopyranoside in 7 ml of water was added 0.463 g of acetic anhydride. The solution was shaken for 5 minutes then taken to dryness. The resulting glass was triturated with ethyl acetate and the solid collected, giving 1.49 g. of the desired intermediate as a white glass.

Workup

  1. customThe resulting glass was triturated with ethyl acetate
  2. customthe solid collected
  3. customgiving 1.49 g

Sources & evidence

ORD record
ord-436dc66fea1f49428eb903f2e7c5ca57
Source dataset
uspto-grants-1984_09
Patent number
US04470976

Reaction notes

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