Monobenzone → 1-(Benzyloxy)-4-[(6-bromohexyl)oxy]benzene

HRID 2417982Notes

Reaction equation

HRID 2417982 reaction equation
[CH2:1]([O:8][C:9]1[CH:14]=[CH:13][C:12]([OH:15])=[CH:11][CH:10]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[Br:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22]Br>C1(C)C=CC=CC=1>[CH2:1]([O:8][C:9]1[CH:10]=[CH:11][C:12]([O:15][CH2:22][CH2:21][CH2:20][CH2:19][CH2:18][CH2:17][Br:16])=[CH:13][CH:14]=1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

4

Reactant 2

HCID 7638MonobenzoneHCID 123681,6-Dibromohexane

Product 1

HCID 134508831-(Benzyloxy)-4-[(6-bromohexyl)oxy]benzene

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

4-Benzyloxyphenol and 1,6-dibromohexane were reacted using conditions reported in Example 15. The reaction time was 4 days and the extraction solvent used was toluene. The crude product was crystallized from hexane to give 1-benzyloxy-4-(6-bromohexyloxy)benzene, mp 72°-3°.

Workup

  1. customThe crude product was crystallized from hexane

Sources & evidence

ORD record
ord-a6cd268966a243e99939ef739c4038d4
Source dataset
uspto-grants-1984_09
Patent number
US04471116

Reaction notes

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