5-((Dimethylamino)methyl)-2-furanmethanol → Orf 17583

HRID 2418041Notes

Reaction equation

HRID 2418041 reaction equation
[CH3:1][NH:2][C:3]1[C:7]([NH:8][CH2:9][CH2:10][SH:11])=[N:6][S:5](=[O:12])[N:4]=1.[CH3:13][N:14]([CH2:16][C:17]1[O:21][C:20]([CH2:22]O)=[CH:19][CH:18]=1)[CH3:15]>Cl>[CH3:13][N:14]([CH2:16][C:17]1[O:21][C:20]([CH2:22][S:11][CH2:10][CH2:9][NH:8][C:7]2[C:3]([NH:2][CH3:1])=[N:4][S:5](=[O:12])[N:6]=2)=[CH:19][CH:18]=1)[CH3:15]

Participants

4

Reactant 2

HCID 849065-((Dimethylamino)methyl)-2-furanmethanolHCID 159612033-Methylamino-4-(2-mercaptoethylamino)-1,2,5-thiadiazole 1-oxide

Product 1

HCID 5486884Orf 17583

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidSolvent

Procedure

When 3-methylamino-4-(2-mercaptoethylamino)-1,2,5-thiadiazole 1-oxide [prepared in Step A] is treated with about one equivalent of 5-dimethylaminomethyl-2-furan-methanol in concentrated hydrochloric acid according to the procedure described in Example 25, Step B, the title compound is thereby produced; identical to the product of Example 18.

Sources & evidence

ORD record
ord-00abdfc7c5134a98bd2ee3deb3f3b704
Source dataset
uspto-grants-1984_09
Patent number
US04471122

Reaction notes

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