Methylamine → HCID 178482520, compound

HRID 2418052Notes

Reaction equation

HRID 2418052 reaction equation
[S:1]1[CH:5]=[CH:4][N:3]=[C:2]1[CH2:6][S:7][CH2:8][CH2:9][NH2:10].COC1C(OC)=NS(=O)(=O)N=1.CO[C:24]1[C:28]([NH:29][CH2:30]CSCC2SC=CN=2)=[N:27][S:26](=[O:40])(=[O:39])[N:25]=1.CN>>[CH3:30][NH:29][C:28]1[C:24]([NH:10][CH2:9][CH2:8][S:7][CH2:6][C:2]2[S:1][CH:5]=[CH:4][N:3]=2)=[N:25][S:26](=[O:40])(=[O:39])[N:27]=1

Participants

5

Reactant 4

HCID 6329MethylamineHCID 122305383,4-Dimethoxy-1,2,5-thiadiazole 1,1-dioxideHCID 129234032-[(Thiazol-2-yl)methylthio]ethylamineHCID 178494334HCID 178494334, compound

Product 1

HCID 178482520HCID 178482520, compound

Procedure

When a methanolic solution of 2-[(thiazol-2-yl)methylthio]ethylamine [prepared according to the procedure described in U.S. Pat. No. 3,950,333] is reacted with 3,4-dimethoxy-1,2,5-thiadiazole 1,1-dioxide and the resultant 3-methoxy-4-{2-[(thiazol-2-yl)methylthio]ethylamino}-1,2,5-thiadiazole 1,1-dioxide treated with methylamine according to the general procedure described in Example 31, the title compound is thereby produced.

Sources & evidence

ORD record
ord-56bca26711d1460d89d96206b71f0efb
Source dataset
uspto-grants-1984_09
Patent number
US04471122

Reaction notes

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