Methylamine → HCID 178482524, compound

HRID 2418075Notes

Reaction equation

HRID 2418075 reaction equation
[CH3:1][N:2]([CH3:13])[C:3]1[O:4][C:5]([CH2:8][S:9][CH2:10][CH2:11][NH2:12])=[N:6][N:7]=1.COC1C(OC)=NS(=O)(=O)N=1.CN(C)C1OC(CSC[CH2:35][NH:36][C:37]2[C:41](OC)=[N:40][S:39](=[O:45])(=[O:44])[N:38]=2)=NN=1.CN>>[CH3:1][N:2]([CH3:13])[C:3]1[O:4][C:5]([CH2:8][S:9][CH2:10][CH2:11][NH:12][C:41]2[C:37]([NH:36][CH3:35])=[N:38][S:39](=[O:45])(=[O:44])[N:40]=2)=[N:6][N:7]=1

Participants

5

Reactant 4

HCID 6329MethylamineHCID 122305383,4-Dimethoxy-1,2,5-thiadiazole 1,1-dioxideHCID 20402177HCID 20402177, compoundHCID 178494337HCID 178494337, compound

Product 1

HCID 178482524HCID 178482524, compound

Procedure

When the above amine is reacted with an equimolar amount of 3,4-dimethoxy-1,2,5-thiadiazole 1,1-dioxide, and the resultant 3-{2-[(2-dimethylamino-1,3,4-oxadiazol-5-yl)methylthio]ethylamino}-4-methoxy-1,2,5-thiadiazole 1,1-dioxide is treated with an excess of methylamine, the title compound is thereby produced.

Sources & evidence

ORD record
ord-cfbf23d5bf4d4589ad681ef35d097352
Source dataset
uspto-grants-1984_09
Patent number
US04471122

Reaction notes

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