Phosphorus oxychloride → 2H-1,2,4,6-Thiatriazine, 3-chloro-2,5-dimethyl-, 1,1-dioxide

HRID 2418128Notes

Reaction equation

HRID 2418128 reaction equation
[CH3:1][C:2]1[NH:3][S:4](=[O:11])(=[O:10])[N:5]([CH3:9])[C:6](=O)[N:7]=1.P(Cl)(Cl)(Cl)(Cl)[Cl:13].P(Cl)(Cl)(Cl)=O>>[Cl:13][C:6]1[N:5]([CH3:9])[S:4](=[O:11])(=[O:10])[N:3]=[C:2]([CH3:1])[N:7]=1

Participants

4

Reactant 3

HCID 24813Phosphorus oxychlorideHCID 24819Phosphorus pentachlorideHCID 178433508HCID 178433508, compound

Product 1

HCID 1588652H-1,2,4,6-Thiatriazine, 3-chloro-2,5-dimethyl-, 1,1-dioxideYield 100%

Conditions

Temperature
110 °C

Procedure

212 parts of 3,6-dimethyl-6H-1,2,4,6-thiatriazin-5-one-1,1-dioxide were introduced into a stirred mixture of 292 parts of phosphorus pentachloride and 1,400 parts of phosphorus oxychloride at room temperature, and the mixture was heated to 110° C. in the course of 30 minutes. The reaction mixture was stirred under reflux for 6 hours and then evaporated down under reduced pressure to give 234 parts (yield: 100% of theory) of 5-chloro-3,6-dimethyl-6H-1,2,4,6-thiatriazine-1,1-dioxide of melting point 86°-90° C. NMR (60 MHz, CDCl3): CH3 --C 2.4δ, CH3 --N 3.68).

Workup

  1. temperatureunder reflux for 6 hours
  2. customevaporated down under reduced pressure

Sources & evidence

ORD record
ord-a4a038a0b0d3494b922539df1df58ad3
Source dataset
uspto-grants-1984_09
Patent number
US04472191

Reaction notes

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