HCID 13338827, compound → HCID 20446049, compound

HRID 2418227Notes

Reaction equation

HRID 2418227 reaction equation
[Cl:1][C:2]1[CH:11]=[CH:10][C:9]([O:12][C:13]([NH:15][CH2:16][C:17]([O:19][CH2:20][CH3:21])=[O:18])=[O:14])=[C:8]2[C:3]=1[CH:4]=[CH:5][CH:6]=[N:7]2>Cl>[ClH:1].[Cl:1][C:2]1[CH:11]=[CH:10][C:9]([O:12][C:13]([NH:15][CH2:16][C:17]([O:19][CH2:20][CH3:21])=[O:18])=[O:14])=[C:8]2[C:3]=1[CH:4]=[CH:5][CH:6]=[N:7]2

Participants

3

Reactant 1

HCID 13338827HCID 13338827, compound

Product 1

HCID 20446049HCID 20446049, compound

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidSolvent

Procedure

5.0 g of ethyl N-(((5-chloro-8-quinolinyl)oxy)carbonyl)glycinate (prepared as described in Example 1) was stirred in 30 ml of 5 N hydrochloric acid at room temperature. A precipitate formed and was collected by filtration and subsequently recrystallized from ethanol to give the desired ethyl N-(((5-chloro-8-quinolinyl)oxy)carbonyl)glycinate hydrochloride salt as pale yellow crystals, m.p. 170° C. (decomposition).

Workup

  1. customA precipitate formed
  2. filtrationwas collected by filtration
  3. customsubsequently recrystallized from ethanol

Sources & evidence

ORD record
ord-062e0bb299624a88ab96f085c32820d9
Source dataset
uspto-grants-1984_09
Patent number
US04472404

Reaction notes

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