反应详情

温度

150 °C

A mixture of 50 g of (III) and 31.7 g of pyrrolidine was heated for 5 hours at 150° C. in an oil bath. The crude product was cooled, and dissolved in CHCl3, and the solution was washed with dilute NaOH and then several times with water. The organic phase was dried over Na2SO4 and concentrated. Distillation of the residue gave 19 g of (IV) of boiling point 148°-150° C./0.1 mbar.

1. washthe solution was washed with dilute NaOH
2. dry with materialThe organic phase was dried over Na2SO4
3. concentrationconcentrated
4. distillationDistillation of the residue