HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2418277Generated: November 3, 2026
Piperidine → N-{3-[2-Bromo-4-(1,1-dimethylpentyl)-phenyl]-2-methylpropyl}-piperidine
https://huagongshe.com/reaction/2418277
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Piperidine | HCID 8082 | — |
| Reactant | 3-[2-Bromo-4-(1,1-dimethyl-pentyl)-phenyl]-2-methylpropyl chloride | HCID 13141994 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | N-{3-[2-Bromo-4-(1,1-dimethylpentyl)-phenyl]-2-methylpropyl}-piperidine | HCID 13142000 | 47.3% |
Reaction Steps
A mixture of 50 g of XIII and 38.3 g of piperidine was heated at 150° C. for 7 hours. The mixture was cooled and then taken up in CHCl3, and the solution was washed with dilute NaOH and then with water, dried over Na2SO4 and concentrated. Distillation of the residue gave 27 g of (XIV) of boiling point 170°-171° C./0.1 mbar.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04472412 |
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| Source dataset | uspto-grants-1984_09 |
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| ORD ID | ord-7900d5bd6d8c488f9b05c40a826845a6 |
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| Source note | uspto-grants-1984_09 |
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