反应详情

温度

150 °C

A mixture of 50 g of XIII and 38.3 g of piperidine was heated at 150° C. for 7 hours. The mixture was cooled and then taken up in CHCl3, and the solution was washed with dilute NaOH and then with water, dried over Na2SO4 and concentrated. Distillation of the residue gave 27 g of (XIV) of boiling point 170°-171° C./0.1 mbar.

1. temperatureThe mixture was cooled
2. washthe solution was washed with dilute NaOH
3. dry with materialwith water, dried over Na2SO4
4. concentrationconcentrated
5. distillationDistillation of the residue