Hydrochloric Acid → HCID 131713686, compound

Participants

Reaction Steps

A mixture of 2.51 g (0.01 mol) 2-methoxy-N-(2,4-dimethylthien-3-yl)-N-(1-butin-3-yl)-acetamide, 1.3 g (0.0325 mol) NaOH and 100 ml methanol are cooled with stirring to 10°, and 2.65 g (0.01 mol) powdered iodine is then slowly added. The mixture is then stirred for 3 hours at room temperature, neutralized with methanolic HCl-solution, and the solvent evaporated to yield, after chromatography, the title compound.

Provenance & Evidence