Sodium Hydroxide → HCID 86739649, compound

Participants

Reaction Steps

10 g (26.26 mmol) of 2-amino-2'-[o-fluoro-α-(hydroxyimino)benzyl]-4'-[1-(hydroxyimino)ethyl]-acetanilide are treated with 3N sodium hydroxide at 50° for 1 hour. The pH of the solution is adjusted to 8 and the precipitated material is filtered off, washed with water and dried at 50° in vacuo over phosphorus pentoxide. There is obtained 2-amino-2'-fluoro-5-[1-(hydroxyimino)ethyl]benzophenone oxime as a foam of melting point ca 165°.

Provenance & Evidence