2,3-Dichlorophenol → HCID 20446172, compound

HRID 2418328Notes

Reaction equation

HRID 2418328 reaction equation
[N+:1]([C:4]1[C:9](Cl)=[CH:8][CH:7]=[CH:6][C:5]=1[CH2:11][C:12]([O:14]CC)=[O:13])([O-:3])=[O:2].[Cl:17][C:18]1[C:23]([Cl:24])=[CH:22][CH:21]=[CH:20][C:19]=1[OH:25].C(=O)([O-])[O-].[K+].[K+]>>[N+:1]([C:4]1[C:9]([O:25][C:19]2[CH:20]=[CH:21][CH:22]=[C:23]([Cl:24])[C:18]=2[Cl:17])=[CH:8][CH:7]=[CH:6][C:5]=1[CH2:11][C:12]([OH:14])=[O:13])([O-:3])=[O:2]

Participants

4

Reactant 3

HCID 113342,3-DichlorophenolHCID 11430Potassium CarbonateHCID 20446267Ethyl 2-(3-chloro-2-nitrophenyl)acetate

Product 1

HCID 20446172HCID 20446172, compoundYield 29.2%

Procedure

A mixture of ethyl 2-(2-nitro-3-chlorophenyl)acetate (10 g.), 2,3-dichlorophenol (7.4 g.), anhydrous potassium carbonate (8.5 g.) and cupric oxide (1 g.) was treated in a similar manner to the above to give 2-[2-nitro-3-(2,3-dichlorophenoxy)phenyl]acetic acid (4.1 g.). mp 178° to 183° C.

Workup

  1. additionwas treated in a similar manner to the above

Sources & evidence

ORD record
ord-d82e0b0621b4467081b4f760db0dd628
Source dataset
uspto-grants-1984_09
Patent number
US04472433

Reaction notes

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