2,4-Dichlorophenol → HCID 20446299, compound

HRID 2418329Notes

Reaction equation

[N+:1]([C:4]1[C:9](Cl)=[CH:8][CH:7]=[CH:6][C:5]=1[CH2:11][C:12]([O:14]CC)=[O:13])([O-:3])=[O:2].[Cl:17][C:18]1[CH:23]=[C:22]([Cl:24])[CH:21]=[CH:20][C:19]=1[OH:25].C(=O)([O-])[O-].[K+].[K+]>>[N+:1]([C:4]1[C:9]([O:25][C:19]2[CH:20]=[CH:21][C:22]([Cl:24])=[CH:23][C:18]=2[Cl:17])=[CH:8][CH:7]=[CH:6][C:5]=1[CH2:11][C:12]([OH:14])=[O:13])([O-:3])=[O:2]

Participants

Reactant 3

HCID 84492,4-Dichlorophenol

HCID 11430Potassium Carbonate

HCID 20446267Ethyl 2-(3-chloro-2-nitrophenyl)acetate

Product 1

HCID 20446299HCID 20446299, compoundYield 17.1%

Procedure

A mixture of ethyl 2-(2-nitro-3-chlorophenyl)acetate (10 g.), 2,4-dichlorophenol (7.4 g.), anhydrous potassium carbonate (8.6 g.) and cupric oxide (1 g.) was treated in a similar manner to the above to give 2-[2-nitro-3-(2,4-dichlorophenoxy)phenyl]acetic acid (2.4 g.).

Workup

additionwas treated in a similar manner to the above

Sources & evidence

ORD record: ord-e435a020dc0a43ff8a6fcd7d189d63f9
Source dataset: uspto-grants-1984_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04472433

Reaction notes

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