Chlorosuccinimide → HCID 20446302, compound

HRID 2418341Notes

Reaction equation

HRID 2418341 reaction equation
[NH2:1][C:2]1[C:7]([O:8][C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=2[Cl:15])=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:16][C:17]([O:19]CC)=O.[Cl:22]N1C(=O)CCC1=O>O1CCOCC1>[O:19]=[C:17]1[CH2:16][C:3]2[C:2](=[C:7]([O:8][C:9]3[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=3[Cl:15])[CH:6]=[C:5]([Cl:22])[CH:4]=2)[NH:1]1

Participants

4

Reactant 2

HCID 31398ChlorosuccinimideHCID 20446151HCID 20446151, compound

Product 1

HCID 20446302HCID 20446302, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

Ethyl 2-[2-amino-3-(2-chlorophenoxy)phenyl]acetate (1.50 g.), N-chlorosuccinimide (700 mg.) and dioxane (30 ml.) were treated in a similar manner to that of the Preparation 31 to give crystals of the captioned compound (0.50 g.), mp 196° to 198° C.

Workup

  1. customof the Preparation 31
  2. customto give crystals of the captioned compound (0.50 g.), mp 196° to 198° C.

Sources & evidence

ORD record
ord-01d41a02544644a98a4685194999e6a5
Source dataset
uspto-grants-1984_09
Patent number
US04472433

Reaction notes

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