Sodium Hydroxide → HCID 20446150, compound

Participants

Reaction Steps

A mixture of ethyl 2-[2-amino-3-(3,5-dichlorophenoxy)phenyl]acetate (6.9 g.), sodium hydroxide (1.6 g.) and water (50 ml.) was treated in a similar manner to that of Example 5-(2). The resultant residue (6.2 g.) was crystallized with a mixture of ethyl acetate and n-hexane to give white crystals of 2-[2-amino-3-(3,5-dichlorophenoxy)phenyl]acetic acid (4.5 g.). mp 113° to 115° C.

Provenance & Evidence