HuagongsheHuagongshe Chemistry Print Report · For research reference only
L-Tryptophan, methyl ester → N-[1-methoxycarbonyl-2-(3-indolyl)-ethyl]-alanyl-L-proline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | L-Tryptophan, methyl ester | HCID 77980 | — |
| Reactant | Sodium cyanoborohydride | HCID 5003444 | — |
| Reactant | (S)-1-(2-Oxopropanoyl)pyrrolidine-2-carboxylic acid | HCID 10130260 | — |
| Product | N-[1-methoxycarbonyl-2-(3-indolyl)-ethyl]-alanyl-L-proline | HCID 53931010 | — |
Reaction Steps
In a manner similar to Example 16 tryptophan methyl ester is condensed with pyruvoyl-L-proline in the presence of sodium cyanoborohydride to yield N-[1-methoxycarbonyl-2-(3-indolyl)-ethyl]-alanyl-L-proline.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04472380 |
| Source dataset | uspto-grants-1984_09 |
| ORD ID | ord-439e3aecbd8e4383bce52cd1ac96b83d |
| Source note | uspto-grants-1984_09 |