Benzaldehyde → Ethyl 2-Propyl-3-hydroxy-3-phenylpropionate

HRID 2418635Notes

Reaction equation

[C:1]([O:7][CH2:8][CH3:9])(=[O:6])[CH2:2][CH2:3][CH2:4][CH3:5].[CH:10](=[O:17])[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1>>[CH2:3]([CH:2]([CH:10]([OH:17])[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)[C:1]([O:7][CH2:8][CH3:9])=[O:6])[CH2:4][CH3:5]

Participants

Reactant 2

HCID 240Benzaldehyde

HCID 10882Ethyl valerate

Product 1

HCID 13594173Ethyl 2-Propyl-3-hydroxy-3-phenylpropionate

Procedure

A 100 milligram sample of the prepared hydroxy-ester is pyrolyzed in a sealed tube at 240°-245° C. for 1 hour. Examination of the pyrolyzate by liquid chromatography indicates that it consists of 60% of unreacted hydroxy-ester and 40% of a 1:1 mixture of ethyl valerate and benzaldehyde.

Sources & evidence

ORD record: ord-e3594e9ac48b4eb3ad5f972ba7f853fa
Source dataset: uspto-grants-1984_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04473085

Reaction notes

Loading…